Name:Spiramycin
CAS No.:8025-81-8
Appearance: White to yellowish powder
Molecular formula:C43H74N2O14
EINECS No.: 232-429-6
Molecular Weight: 843.0527
Density:1.21g/cm3
Boiling point: 913.7 ° C at 760 mmHg
Flash point:506.4 ° C
Steam pressure:0mmHg at 25 ° C
Shelf life:24 months
Description:
Spiramycin is white or yellowish powder with slight taste; Micro moisture absorption; It is soluble in methanol, ethanol, acetone or ether, almost insoluble in water, and insoluble in petroleum ether. It is a macrolide antibiotic obtained from Streptomyces ambofaciens culture medium. Spiramycin is the acetate of acetylspiramycin, which is deacetylated after oral administration and shows strong antibacterial effect. Spiramycin is a kind of strong bacteriostatic agent, which has bactericidal effect only at a very high concentration.
Application:
Spiramycin can be used to treat ear, nose, throat and respiratory tract infections caused by gram-positive bacteria and some gram-negative bacteria, such as acute bronchitis, acute attack of acute bronchitis, pneumonia, scarlet fever, tonsillitis, otitis media, periodontitis and acute sinusitis. This product can also be used to treat non gonococcal urethritis. This product has strong antibacterial effect and post antibacterial effect (PAE) in vivo, can enhance the phagocytosis of phagocytes, and is widely distributed in the body. The concentration of this product in the tissue and cells is higher than erythromycin, and the side effects are less than erythromycin.
Specification:
Product Name
|
Spiramycin Adipate
|
Serial no.
|
2021790032
|
Batch No.
|
210916003
|
Quantity
|
301.30KG
|
MFG Date
|
2021-09-08
|
EXP Date
|
2024-09-07
|
According to
|
Local Standard
|
Report Date
|
2021-09-15
|
|
Test Items
|
Specification
|
Results
|
Characteristics
|
A white or almost white crystalline powder.
|
Conform
|
Identification
|
Ultraviolet spectrophotometry:λmax=232nm
|
Conform
|
Chromogenic reaction: Positive
|
Positive reaction
|
Specific Optical Rotation
|
-68°~-73°
|
-70°
|
pH
|
5.0~7.0
|
6.0
|
Loss on drying
|
≤3.0%
|
2.4%
|
Residue on lgnition
|
≤0.10%
|
0.08%
|
Heavy metals
|
≤20ppm
|
Conform
|
Assay
(on dried basis)
|
Assay as Spiramycin Base 80.0%~88.0%
|
82.8%
|
Assay as Adipic Acid 13.0%~15.0%
|
13.0%
|
Microbiological Assay Not less than 3400 u/mg
|
3826u/mg
|
Conclusion
|
The above certificate of analysis is in compliance with Local Standard.
|
Package:
Payment Method: L/C、D/A、T/T
Shipping Ports: Shanghai, Ningbo, Qingdao, Tianjin And Other Ports In China.
Type Of Shipping: Express、Ocean freight、Land freight、Air freight
Our Service:
1. Reply within 12 hours.
2. High-quality products and the most reasonable price
3. Data and chemical technology support.
4. Professional team service
5. Customiszed production for different package