Description:
Piroxicam, also known as feldene, is an organic compound, chemical formula C15H13N3O4S, mainly used as antipyretic analgesic, non-steroidal anti-inflammatory drugs.Piroxicam is a non-steroidal anti-inflammatory drug with analgesic, anti-inflammatory and antipyretic effects. By inhibiting cyclooxygenase, it can reduce the synthesis of prostaglandins in local tissues, inhibit the chemotaxis of leukocytes and the release of lysosomal enzymes, and exert pharmacological effects.Clinically, it can be used to relieve various arthritis, fever, gout, toothache, migraine, muscle strain, pain after surgery and other corresponding symptoms.
Application:
Piroxicam is a commonly used Non-Steroidal Anti-Inflammatory Drug (AID) with analgesic, anti-inflammatory and antipyretic effects. The following is a detailed description of the action of Piroxicam:
1.Analgesic effect: Piroxicam reduces the stimulation of pain receptors by inhibiting the synthesis of prostaglandins in the body, thus achieving the analgesic effect. It is widely used to treat various types of pain, including pain symptoms such as arthritis, rheumatoid arthritis, and osteoarthritis.
2.Anti-inflammatory effect: Piroxicam reduces inflammation by inhibiting the production and release of inflammatory mediators, such as prostaglandins and interleukins. It can be used to treat inflammatory diseases such as arthritis, rheumatoid arthritis and ankylosing spondylitis.
3.Antipyretic effect: Piroxicam can inhibit the synthesis of prostaglandins in the brain, reduce the sensitivity of the thermoregulatory center to thermal substances, and play an antipyretic effect. It is often used to treat fever caused by viral infections such as colds and flu.
In addition, Piroxicam has also been studied for anti-tumor therapy, because it can inhibit tumor angiogenesis and promote tumor cell apoptosis, and has a certain inhibitory effect on some tumors. However, the application is still in the research stage and has not yet been widely used in the clinic.