Neomycin Sulphate

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Neomycin Sulphate

2022-02-14

Neomycin sulfate is an aminoglycoside antibiotic. This product has good antibacterial effect on Staphylococcus (methicillin sensitive strain), Corynebacterium, Escherichia coli, Klebsiella, Proteus and other Enterobacteriaceae bacteria. Cocci, Enterococcus and other poor activity. Pseudomonas aeruginosa and anaerobic bacteria are resistant to this product. Bacteria have partial or complete cross-resistance to streptomycin, neomycin, kanamycin and gentamicin.

Physical and chemical properties: Neomycin sulfate is white or off-white powder; odorless; very easy to get wet; the aqueous solution exhibits dextrorotatory properties. The product is easily soluble in water and almost insoluble in ethanol, ether, acetone or chloroform.

Adverse reactions: 1. It can cause loss of appetite, nausea, diarrhea, etc., but long-term application (over 10 weeks) does not affect the synthesis of vitamin K. 2. Hearing loss, tinnitus, or fullness in the ears are rarely found; dizziness or unsteady gait; significantly reduced urine output or frequency, or extreme thirst. 3. Occasionally, it can cause intestinal mucosal atrophy and lead to malabsorption syndrome and fatty diarrhea, and even pseudomembranous colitis.

Application field: Neomycin sulfate is a broad-spectrum antibiotic with good effect on Staphylococcus aureus, Bacillus diphtheriae and Bacillus anthracis.

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