Chloramphenicol hydrochloride is in a golden or yellow crystalline form; No odor, bitter taste; Gradually darken when encountering light colors. It is slightly soluble in water or ethanol, but almost insoluble in acetone, ether, or chloroform.
Antibacterial effect
Chloramphenicol hydrochloride has a wide antibacterial range and has inhibitory effects on various bacteria, certain rickettsias, mycoplasma, spirochetes, and protozoa; Mainly used for bacterial infections that are resistant to penicillin, such as pneumonia and staphylococcal sepsis, typhus, mycoplasma pneumonia, amoebic dysentery, etc.
Mechanism of action
Chloramphenicol is a tetracycline antibiotic, and many Gram positive bacteria, as well as Rickettsia, Mycoplasma, Chlamydia, Atypical Mycobacterium, and Spirochetes, are sensitive to this product. Enterococcus is resistant to it, and there is cross resistance between this product and different varieties of tetracyclines. One of the main mechanisms of action of aureomycin eye ointment is to inhibit the synthesis of bacterial proteins, which has an inhibitory effect on common Gram positive bacteria and Chlamydia trachomatis in the eyes.
purpose
Chloramphenicol hydrochloride can bind to tRNA, thereby achieving antibacterial effects. Can be used for bacterial conjunctivitis, wheat swelling, and bacterial blepharitis. It is also used to treat trachoma.
side effect
Oral administration can easily cause gastrointestinal reactions such as nausea, vomiting, diarrhea, etc; In addition, broad-spectrum antibiotics such as chloramphenicol can cause secondary infections such as Staphylococcus and Candida due to the elimination of sensitive bacteria and the proliferation of non sensitive bacteria or fungi during prolonged use.
matters needing attention
This product is contraindicated for individuals with allergies and should be used with caution for those with allergies. It is not suitable for long-term continuous use. If symptoms do not improve within 5 days, medication should be stopped promptly for medical attention.