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veterinary drug
Application and Synthesis Method of Maduramycin Ammonium Salt
2023-09-08 15:56:01
Maduramycin ammonium salt is a white crystalline powder with a melting point of 165-167 ℃. It is insoluble in water and soluble in organic solvents. Due to its wide spectrum of anti coccidiosis and low susceptibility to drug resistance, it is widely used, but its dosage is very small. Currently, according to our national regulations, Maduramycin ammonium salt is added in feed at a dosage of 5mg/kg for the prevention of chicken coccidiosis.
application
Maduramycin ammonium is an anti coccidiosis drug developed by Cyanoammonium Corporation in the United States. It has a broad spectrum of anti coccidiosis and is currently one of the most effective anti coccidiosis drugs. Maduramycin is a monovalent glycoside polyether ion carrier antibiotic. It is currently the most effective and lowest concentration polyether anti coccidian drug, widely used in broiler chickens to resist coccidia. The anti coccidiosis mechanism of maduramycin is the same as that of monensin.
Anti coccidian efficacy
Experiments have shown that maduramycin has inhibitory and killing effects on early sporozoites, trophozoites, and 1st generation schizoites of coccidia. Maduramycin ammonium is mainly used for coccidiosis in broiler chickens. According to experiments, it has good inhibitory and killing effects on giant, toxic, tender, pile type, and Eimeria brucei coccidiosis in chickens. Its anti coccidiosis effect is better than other anti coccidiosis drugs such as monensin, salinomycin, and methylsalinomycin.
Chemical properties
White crystalline powder, melting point 165-167 ℃, insoluble in water, soluble in most organic solvents.
Purpose
Maduramycin ammonium salt is effective as an anticoccidial agent against Escherichia coli, Escherichia coli, Escherichia coli, Escherichia coli, Escherichia coli, Escherichia coli, Escherichia coli, and Escherichia coli. It also has an inhibitory effect on most Gram positive bacteria. Can be used for chicken feed, with a dosage of 5 (500 × 104U) g/t, prohibited during egg laying period, with a 5-7 day discontinuation period; When the dosage exceeds 6g/t, growth is significantly inhibited, and caution should be exercised when mixed with other drugs.
Purpose
Usage: Coccidioside, killing parasites in the host body. According to the US FDA regulations, only for broiler chickens, 4.54-5.554g (5-6E-6) should be added to each feed. The advantage of this product is that it has a small dosage and is non-toxic to equine animals.
Purpose
Used for the prevention and control of chicken coccidiosis
Production method
Produced by fermentation of microorganisms isolated from soil (Actinomadurayumaensis).
 
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