Many pharmaceutical companies in the veterinary drug market are producing and selling neomycin sulfate products, and counterfeit and substandard products are always two types of commodities that are repeatedly prohibited in the free market economy. Therefore, selecting high-quality genuine neomycin sulfate has become the key and prerequisite for effective medication.
How to choose
Firstly, let's talk about those fake neomycin sulfates. When people use neomycin sulfate, they mostly face the problem of "neomycin sulfate soluble powder"; Because its basic production technology and condition requirements are not high, it is most common in the veterinary drug market.
Considering that the original drug of neomycin sulfate is easily soluble in water, once you purchase a poorly water-soluble or insoluble neomycin sulfate veterinary product, it means you have purchased a "fake neomycin sulfate veterinary product"!
Moreover, the true and qualified color of neomycin sulfate raw material is white or almost white; If the neomycin sulfate veterinary drug product you purchased is yellow or light yellow, or even other colors, it means you have purchased a "fake neomycin sulfate veterinary drug product" again!
Of course, the identification of fake neomycin sulfate is not only based on its water solubility and color, but also on many aspects. Because some identification requires professional testing instruments, we will not explain them one by one.
Secondly, let's talk about the "substandard" neomycin sulfate. Another expression for substandard products is poor quality, such as black and white discoloration of drugs, caking and gas production of drugs, almost no antibacterial zone in drug potency testing, or the antibacterial zone does not meet the standard (the country has clear standards for this), and so on. These are all manifestations of poor quality of neomycin sulfate products.
Once a user purchases such a sulfated neomycin veterinary drug product, it not only has no effect when used, but also causes secondary damage to the digestive system of diseased livestock and poultry due to the large amount of toxic by-products produced in low-quality sulfated neomycin products, exacerbating or worsening the condition, and even causing mass deaths of livestock and poultry.
Efficient medication
So if we choose high-quality neomycin sulfate veterinary drug products, how can we use them well and achieve "efficient" therapeutic effects?
This requires understanding the pharmacology and antibacterial spectrum of neomycin sulfate, as beyond its effective effects and pathogenic spectrum, even the best drugs will be ineffective in treatment.
Neomycin sulfate is an aminoglycoside antibiotic. It has good antibacterial effects on digestive system sensitive bacteria such as Escherichia coli, Salmonella, Pasteurella, Staphylococcus (methicillin sensitive strains), Proteus, etc. in the clinical treatment of livestock and poultry veterinarians, but has poor antibacterial activity against various Streptococcus, Streptococcus pneumoniae, Enterococcus, etc. Pseudomonas aeruginosa and anaerobic bacteria are resistant to neomycin sulfate.
Neomycin sulfate is administered orally to livestock and poultry, but it is rarely absorbed (within 5%) under normal circumstances. However, if a large dose is continuously taken orally, especially when there are ulcers or inflammations in the intestinal mucosa, the gastrointestinal tract of livestock and poultry can still absorb a considerable amount of neomycin sulfate. Especially when the renal function of livestock and poultry decreases, the excretion of neomycin sulfate entering the body slows down, and the blood drug concentration in the body can significantly increase at this time.
For grassroots veterinarians and frontline drug users, it is important not to inject neomycin sulfate for systemic administration, as