Product details Oxytetracycline hydrochloride CAS NO.2058-46-0 as Antibiotic drugs origin from China. Anhui Sinotech company strictly select GMP products, support customer registration , and provide professional services to chemical customers in the global market.Purchase Oxytetracycline hydrochloride CAS NO.2058-46-0,inquiry Anhui Sinotech . Name:                Oxytetracycline hydrochloride              CAS No.:               2058-46-0 Molecular formula:   C22H25ClN2O9 Molecular Weight:      496.8949 Description: GMP Veterinary Oxytetracycline hydrochloride CAS NO.2058-46-0 99%purity is Yellow crystalline powder,odorless, slightly bitter taste; slightly moisturizing; the color becomes dark under sunlight, and it is easy to destroy and fail when dissolved in alkali. This product is soluble in water, slightly soluble in ethanol, and insoluble in chloroform or ether. Application Oxytetracycline hydrochloride CAS NO.2058-46-0 can quickly inhibit the growth and reproduction of bacteria, that is, Oxytetracycline hydrochloride can slow down the speed of bacterial growth and reproduction, and greatly extend the growth and reproduction cycle of individual bacteria. But Oxytetracycline hydrochloride cannot kill bacteria directly Specification Oxytetracycline hydrochloride CAS NO.2058-46-0 Tests Specifications Results Appearance Yellow, crystalline powder. Conforms Solubility Freely soluble in water,sparingly soluble in ethanol,solutions in water become turbid on standing.owning to the precipitation of Oxytetracycline Conforms Identification A: Thin-layer chromatography B: Color reaction C: Chlorides reaction Conforms pH 2.3 to 2.9 2.5 Sulfated ash ≦ 0.2% 0.17% Light -absorbing impurities (430nm) ≦0.50 0.12 Light -absorbing impurities (490nm) ≦ 0.20 0.13 Water ≦ 2.0% 0.8% Related substances: Impurity A: NMT 0.5% 0.12% Impurity B: NMT 1.0% 0.44% Impurity C: NMT 2.0% 0.78% Impurity D: NMT 0.2% 0.02% Impurity E: NMT 0.2% 0.02% Any other impurity：NMT 0.1% 0.05% Total impurities：NMT3.5% 1.47% Residual Methanol ≦ 0.3% 0.11% Assay (anhydrous substance) 95.0% to 102.0% 98.0% Conclusion: Tested according to BP2018, the results meet the standard requirements.   Package Oxytetracycline hydrochloride CAS NO.2058-46-0

Tylosin tartrate CAS NO.1405-54-5 as Antibiotic drugs origin from China. Anhui Sinotech company strictly select GMP products, support customer registration , and provide professional services to chemical customers in the global market.Purchase Tylosin tartrate CAS NO.1405-54-5,inquiry Anhui Sinotech . Name:     Tylosin tartrate           CAS No.:    1405-54-5  Molecular formula:   C50H83NO23 molecular structure: Molecular Weight:    1066.1869 Description: Veterinary API Tylosin tartrate CAS NO.1405-54-5  is almost white powder.This product belongs to special antibiotics for macrolide animals, has special effects on mycoplasma, and is used as the first choice drug against mycoplasma Application: Tylosin tartrate CAS NO.1405-54-5,Its mechanism of action mainly plays a role of sterilization by hindering the synthesis of bacterial proteins. This product is easily absorbed in the body, excreted quickly, and has no residue in the tissue. Specification：Tylosin tartrate CAS NO.1405-54-5 Items Standard Results Conclusion Appearance White to slightly yellow powder   almost white powder   Complies Identification It gives the positive reaction It gives the positive reaction Complies It gives the positive reaction It gives the positive reaction Complies The retention time of the tylosion A peak in the chromatogram of the test solution correspond to that in the chromatogram of the reference solution The retention time of the tylosion A peak in the chromatogram of the test solution correspond to that in the chromatogram of the reference solution Complies It gives the positive reaction It gives the positive reaction Complies Tests pH pH value 5.0-7.2 5.7 Complies Tyramine Complies complies Complies Loss on drying Not more than 4.2% 2.4% Complies Residue on ignition Not more than 2.5% 0.23% Complies Heavy metals Not more than20ppm Less than 20ppm Complies Content of Tylosin Tylosins A≥82% 89% Complies Tylosins A+B+C+D≥95% 97% Complies Assay Assay(dried basis) ≥830u/mg(dried basis) 928u/mg(dried basis) Complies Assay(wet basis) - 906u/mg(wet basis) Complies Conclusion:Tested according to in-house specification QS-0002-01,it complies with the requirements Package Tylosin tartrate CAS NO.1405-54-5

Oxytetracycline HCL CAS NO.2058-46-0 as Antibiotic origin from China. Anhui Sinotech company strictly select GMP products, support customer registration , and provide professional services to chemical customers in the global market.Purchase Oxytetracycline HCL CAS NO.2058-46-0,inquiry Anhui Sinotech . Name:    Oxytetracycline HCL              CAS No.:   2058-46-0 Molecular formula:   C22H25ClN2O9 molecular structure:   Molecular Weight:      496.8949 Description1: Oxytetracycline HCL CAS NO.2058-46-0 99% purity is yellow, crystalline powder.The antibacterial spectrum and application are the same as tetracycline. This product is slightly better than tetracycline in the treatment of intestinal infection, including amoebic dysentery Description2: GMP API OTC HCL CAS NO.2058-46-0 is Yellow crystalline powder,is a broad-spectrum bacteriostatic agent, belonging to the class of antibiotics Description3: GMP Veterinary Oxytetracycline hydrochloride CAS NO.2058-46-0 99%purity is Yellow crystalline powder,odorless, slightly bitter taste; slightly moisturizing; the color becomes dark under sunlight, and it is easy to destroy and fail when dissolved in alkali. This product is soluble in water, slightly soluble in ethanol, and insoluble in chloroform or ether.   Application1 Veterinary raw materials Oxytetracycline HCL CAS NO.2058-46-0,It is mainly used for treatment, paratyphoid, pig lung disease, asthma, piglet diarrhea, uterine cavity inflammation, Leptospira, protozoa, etc, Application2 API OTC HCL CAS NO.2058-46-0 can quickly inhibit the growth and reproduction of bacteria. API OTC HCL CAS NO.2058-46-0 can slow down the speed of bacterial growth and reproduction, and greatly extend the growth and reproduction cycle of individual bacteria. API OTC HCL CAS NO.2058-46-0 cannot kill bacteria directly Application3 Oxytetracycline hydrochloride CAS NO.2058-46-0 can quickly inhibit the growth and reproduction of bacteria, that is, Oxytetracycline hydrochloride can slow down the speed of bacterial growth and reproduction, and greatly extend the growth and reproduction cycle of individual bacteria. But Oxytetracycline hydrochloride cannot kill bacteria directly    Specification：Oxytetracycline HCL CAS NO.2058-46-0 Tests Specifications Results Appearance Yellow, crystalline powder. Conforms     Solubility Freely soluble in water,sparingly soluble in ethanol,solutions in water become turbid on standing.owning to the precipitation of Oxytetracycline     Conforms   Identification A: Thin-layer chromatography B: Color reaction C: Chlorides reaction   Conforms pH 2.3 to 2.9 2.5 Sulfated ash ≦ 0.2% 0.17% Light -absorbing impurities (430nm) ≦0.50 0.12 Light -absorbing impurities (490nm) ≦ 0.20 0.13 Water ≦ 2.0% 0.8%       Related substances: Impurity A: NMT 0.5% 0.12% Impurity B: NMT 1.0% 0.44% Impurity C: NMT 2.0% 0.78% Impurity D: NMT 0.2% 0.02% Impurity E: NMT 0.2% 0.02%   Any other impurity：NMT 0.1% 0.05%   Total impurities：NMT3.5% 1.47% Residual Methanol ≦ 0.3% 0.11% Assay (anhydrous substance) 95.0% to 102.0% 98.0% Conclusion: Tested according to BP2018, the results meet the standard requirements.   Packing：Oxytetracycline HCL CAS NO.2058-46-0  

Tilmicosin Phosphate CAS NO.137330-13-3 as Antibiotic drugs origin from China. Anhui Sinotech company strictly select GMP products, support customer registration , and provide professional services to chemical customers in the global market.Purchase Tilmicosin Phosphate CAS NO.137330-13-3,inquiry Anhui Sinotech . Name:                Tilmicosin Phosphate       CAS No.:               137330-13-3 Molecular formula:   C20H22N2O4 molecular structure: Molecular Weight:      354.3997 Description: Veterinary API Tilmicosin Phosphate CAS NO.137330-13-3 is pale yellow powder, is a macrolide antibiotic, an upgraded product of tylosin phosphate, specifically for veterinary use. Non-toxic, no residue, strong effect and safe. Application Tilmicosin Phosphate CAS NO.137330-13-3 is a macrolide antibiotic and an upgraded product of Tylosin Phosphate, which is specially used in veterinary medicine. This product is non-toxic, residue-free, effective and safe. It mainly treats respiratory diseases caused by Mycoplasma, infectious pleural pneumonia caused by Actinobacillus and Pasteurella multocida and mammary gland infections of lactating animals. Its medicinal effect is 4-8 times that of tylosin phosphate. At the same time, it has the advantages of convenient use and less incompatibility. Specification：Tilmicosin Phosphate CAS NO.137330-13-3 Item Specification Test Results Description Off-white to pale yellow powder,have moisture abosorption characte.Freely soluble in water, insoluble in acetonitrile pale yellow powder Identification (1)The retention times of the major peaks in the chromatogram of the Assay preparation correspond to those of the Tilmicosin Standard preparation,as obtained in the assay. Complies (2)The product aqueous solution appear phosphate Identification reaction Complies Water Not more than 5.0% 3.3% PH 5.5-7.5 6.3 Solution Clarity Solution should be clear,if not clear,shallower than no 1 turbidity standard Complies Related Substances Any Individual impurity(on anhydrous basis) Not more than 4.0% 3.1% Total impurities(on anhydrous basis) Not more than 10.0% 6.2% Component Cis-isomers 82.0%-88.0% 85.4% Trans-insomers 12.0%-18.0% 14.6% Assay(on anhydrous basis) Not less than 75.0% 79.7% Conclusion According to the “enterprise standard”test,result are consistent with the provision of   Package Tilmicosin Phosphate CAS NO.137330-13-3   

Ciprofloxacin HCL CAS NO.93107-08-5  as antibiotic drugs origin from China. Anhui Sinotech company strictly select GMP products, support customer registration , and provide professional services to chemical customers in the global market.Purchase Ciprofloxacin HCL CAS NO.93107-08-5 ,inquiry Anhui Sinotech .   Name:                Ciprofloxacin HCL     CAS No.:               93107-08-5 Molecular formula:   C17H18FN3O3·HCl molecular structure: Molecular Weight:      367.8 Description: API Veterinary Ciprofloxacin HCL CAS NO.93107-08-5 is faintly yellowish crystalline powder  ,It has broad antibacterial spectrum and strong antibacterial activity, and is effective for both Gram-positive bacteria and Gram-negative bacteria, as well as Pseudomonas aeruginosa, with few adverse reactions Application： Ciprofloxacin HCL CAS NO.93107-08-5,It is mainly used in chronic respiratory tract, Escherichia coli, infectious rhinitis, avian cholera, avian typhoid, etc Ciprofloxacin HCL CAS NO.93107-08-5, It is suitable for urinary tract infection, moderate and severe respiratory tract infection, intestinal infection, skin and soft tissue infection, septicemia and intraperitoneal infection caused by sensitive bacteria Specification：Ciprofloxacin HCL CAS NO.93107-08-5 Tests Acceptance Criteria Results Description Appearance Faintly yellowwish to light yellow crystalline powder Faintly yellowwish crystalline powder Solubility Sparingly soluble in water,slightly solublein acetic acit and in methanol;very slight soluble in dehydrated alcohol;practically insoluble in acetone,in acetonitrile,in ethyl acetete,in hexane,and in methylene chloride. / Identificaion 1)IR:Conforms to the spectrum of Ciprofloxacin Hydrochloride RS 2)HPLC:The retention time of the major peak of the Sample solution corresponds to that of the Standard solution, as obtaind in the Assay. 3)Responds to the tests for chloride. Conforms Ph 3.0-4.5(25mg/ml solution in water) 3.7 Water 4.7-6.7 5.9% Residue on ignition ≤0.1% ＜0.01% Organic impurities Ciprofloxacin ethylenediamine analog ≤0.2% 0.06% Fluoroquinolonic acid ≤0.2% 0.02% Any other individual impurity ≤0.2% 0.05% The sum of all impurities ≤0.5% 0.16% Assay 98.0%-102.0%of C17H18 FN3O3’HCL(Calculate on the anhydrous basis) 100.3% Residue solvents (1)Ethanol ≤5000ppm 415ppm (2)Toluene ≤890ppm Not detected Conclusion:Conforms to USP42 specification for Ciprofloxacin Hydrochloride The elemental im purity is not intentionally added in the manufacturing process.The residue of class I elements(As,Cd,Hg,Pb)and class2A(Co,Ni,V)are meet the requiremets.      Package Ciprofloxacin HCL CAS NO.93107-08-5

Enrofloxacin BASE CAS NO.93106-60-6  as antibiotic drugs origin from China. Anhui Sinotech company strictly select GMP products, support customer registration , and provide professional services to chemical customers in the global market.Purchase Enrofloxacin BASE CAS NO.93106-60-6 ,inquiry Anhui Sinotech .   Name:     Enrofloxacin BASE     CAS No.:    93106-60-6 Molecular formula:   C19H22FN3O3 molecular structure: Molecular Weight:      359.4 Description1: Antibacterial raw materials Enrofloxacin BASE CAS NO.93106-60-6 belongs to tetracycline antibiotics, and belongs to broad-spectrum antimicrobial agents. It has antibacterial effect on Gram-positive bacteria, negative bacteria and mycoplasma. It has been used in the control of vibriosis and colibacillosis in cultured fish. Description2: Veterinary Enrofloxacin BASE CAS NO.93106-60-6  is a kind of Slightly yellow crystalline powder needle powder, odorless, tasteless, soluble in acid or alkaline conditions, slightly soluble in dimethylformamide and chloroform, slightly soluble in methanol and insoluble in water. The color of the product is deepened after a long time of illumination. It is easy to absorb moisture and agglomerate when stored in the place with high relative humidity. Application1 Enrofloxacin BASE CAS NO.93106-60-6, It has strong antibacterial activity against all pathogenic bacteria of aquatic animals. It is effective for severe infection caused by drug-resistant pathogens and has no cross resistance with other antibiotics.  Enrofloxacin BASE CAS NO.93106-60-6,It has bactericidal effect on Escherichia coli, Klebsiella, Salmonella, proteus, Pseudomonas aeruginosa, Haemophilus, Pasteurella multocida, Pasteurella haemolytica, Staphylococcus aureus, Streptococcus, etc. Application2 Enrofloxacin BASE CAS NO.93106-60-6 is a new type of veterinary antibacterial drug with wide spectrum and high efficiency has special effect on Gram-positive bacteria, Gram-negative bacteria and mycoplasma Enrofloxacin BASE CAS NO.93106-60-6 is quinolones for livestock and aquatic products, with broad-spectrum antibacterial activity and strong permeability    Specification：Enrofloxacin BASE CAS NO.93106-60-6   Tests Acceptance Criteria Results Description Appearance Slightly yellow or pale orange-yellow crystalline powder,odorless,slightly bitter;The crystals gradually become orange-red under day light Slightly yellow crystalline powder Solubility Freely soluble in chloroform,sparingly soluble in dimethyl-formamide,slightly soluble in sodium hydroxide TS,very slightlysoluble in water. / Melting range 221-226℃ 223.0-224.5℃ Identificaion HPLC:The retention time of the major peak os the Sample solution corresponds to that of the Standard solution. Conforms IR:Conforms to the reference spectrum. Conforms Clarity of solution Clear(1g/20ml in  0.5mol/L NaOH Solution) Conforms Colour of solution (1g/20ml in  0.5mol/L NaOH Solution)Not more intensely coloured than Y4 or GY4 Conforms Fluoroquinolonic acid ≤0.2% ＜0.2% (HPLC) Related substances （1）Ciprofloxacin ≤0.5% 0.05% （2）Any other single ≤0.3% 0.11% （3）Total impurities ≤0.7% 0.16% Loss on drying ≤0.5% 0.05% Residue on ignition ≤0.2% 0.01% Heavy metals ≤20ppm ＜20ppm Assay ≥99.0%（Dried substance） 100.4% Conclusion:Conforms to Chinese Veterinary Pharmacopeia2015(1)specification for enrofloxacin After risk evaluation,elemental impurities meet the requirements.    Package Enrofloxacin BASE CAS NO.93106-60-6

Sulfamethazine Sodium CAS NO.1981-58-4 as antibiotic drugs origin from China. Anhui Sinotech company strictly select GMP products, support customer registration , and provide professional services to chemical customers in the global market.Purchase Sulfamethazine Sodium CAS NO.1981-58-4 ,inquiry Anhui Sinotech .   Name:  Sulfamethazine Sodium     CAS No.: 1981-58-4 Appearance：milky white crystalline powder Molecular formula:   C12H13N4NaO2S Molecular Weight:      300.312 Density: 1.392g/cm3 Melting point: 176ºC Boiling point: 526.2ºC at 760mmHg Flash point: 272.1ºC Storage conditions: 2-8ºC Vapor pressure: 3.64E-11mmHg at 25°C Molecular structure:     Description: Sulfamethazine Sodium CAS NO.1981-58-4 is white or milky white crystalline powder, odorless or almost odorless, easily soluble in water and slightly soluble in ethanol. Application： Sulfamethazine Sodium CAS NO.1981-58-4 is a sulfa drug used for infections caused by meningitis, pneumococcus, hemolytic streptococcus and certain gram-negative bacilli. It is used as a feed additive to prevent and treat the infection of Staphylococcus and Streptococcus hemolyticus, that is, it mainly treats avian cholera, avian typhoid fever, and chicken coccidiosis.

Anhui Sinotech company strictly select GMP products, support customer registration , and provide professional services to chemical customers in the global market.Purchase Potassium Sorbate CAS NO.24634-61-5,inquiry Anhui Sinotech .

Anhui Hicare Biotech Co.,Ltd strictly select food additives products, support customer registration , and provide professional services to customers in the global market.Purchase Saccharin Sodium 8-12 Mesh CAS NO.:128-44-9,inquiry Anhui Hicare Biotech Co.,Ltd.      Name:  Saccharin Sodium 8-12 Mesh CAS No.:  128-44-9 Molecular formula: C7H4NO3SNa Melting point : >300°C storage temp : 0-6°C Odor : odourless or with a faint, aromatic odour Water Solubility : >=10 g/100 mL at 20 ºC Molecular structure: Description: Saccharin sodium 8-12 mesh CAS NO.: 128-44-9, the sweetness is 200-500 times that of sucrose, generally 300 times. It is easily soluble in water, slightly soluble in ethanol, and the aqueous solution is slightly alkaline. It has low calories and is not absorbed by the human body, and can be automatically excreted in urine and feces. It is used as a sugar substitute for patients with obesity, hyperlipidemia, diabetes and dental caries. In addition, it can also be used as brightener for electroplating nickel and chromium, blood circulation measuring agent, penetrant, etc., with a wide range of uses.  Application： Saccharin Sodium 8-12 Mesh CAS NO.:128-44-9 is mainly used as an additive for different products in the food industry. It is used as a low-calorie sweetener and stabilizer in various foods and beverages. In bakeries, it is used to increase the sweetness of baked goods, breads, biscuits and muffins. Because of its fast dissolving properties in water, it is used as an artificial sweetener in carbonated drinks and soda water. Specification: CERTIFICATE OF ANALYSIS Package：

Anhui Sinotech company strictly select GMP products, support customer registration , and provide professional services to chemical customers in the global market.Purchase Saccharin Sodium 20-40 Mesh CAS NO.:128-44-9,inquiry Anhui Sinotech .   Name:  Saccharin Sodium 20-40 Mesh CAS No.:  128-44-9 Appearance: Crystalline particles Molecular formula: C7H4NO3SNa Odor : odourless or with a faint, aromatic odour Water Solubility : >=10 g/100 mL at 20 ºC Molecular structure: Description: Saccharin sodium 20-40 mesh CAS NO.: 128-44-9 is an artificial or non-nutritive sweetener, white crystalline powder, the sweetness is 200-700 times that of sucrose, but the aftertaste is bitter and astringent. It is easily soluble in water, slightly soluble in ethanol, and the aqueous solution is slightly alkaline. It has low calories and is not absorbed by the human body, and can be excreted automatically with urine and feces. Used as a sugar substitute for patients with obesity, hyperlipidemia, diabetes and dental caries. Sodium saccharin is widely used in the production of various foods and medicines, including soft drinks, candies, biscuits, jams, chewing gum, canned fruits, medicines and toothpaste. Application： Sodium saccharin 20-40 mesh CAS NO.: 128-44-9 is the most commonly used salt to formulate the soluble form of this sweetener. It can be used in toothpaste, mouthwash, diet soda, syrup, baked goods, ice cream and other sweets and beverages. Although saccharin sodium is best known for its use in food, it is also used in the chemical and agricultural industries as an auxiliary for the production of herbicides and pesticides. It is also used as part of the solution used to coat metals such as gold and nickel. Specification: CERTIFICATE OF ANALYSIS Package

Anhui Sinotech company strictly select GMP products, support customer registration , and provide professional services to chemical customers in the global market.Purchase Saccharin Sodium 40-80 Mesh CAS NO.:128-44-9,inquiry Anhui Sinotech .   Name:  Sodium saccharine 40-80 Mesh             CAS No.:  128-44-9 Appearance: white crystalline powder Specification:5-8Mesh,8-12Mesh,20-40Mesh,40-80Mesh Molecular formula: C7H4NO3S Molecular Weight:  182.1771 Melting point: >300℃ Boiling point: 438.9°C at 760 mmHg Molecular structure: Description: Sodium Saccharin 40-80 mesh CAS NO.: 128-44-9 White crystalline powder, 200-500 times sweeter than sucrose, easily soluble in water, slightly soluble in ethanol, and slightly alkaline in aqueous solution. It has low calories and is not absorbed by the human body, and can be excreted automatically with urine and feces. It is used as a sugar substitute for patients with obesity, hyperlipidemia, diabetes and dental caries. Used in the production of various foods and medicines. Application： Sodium saccharin 40-80 mesh CAS NO.: 128-44-9 Food: general cold drinks, beverages, jelly, popsicles, pickles, preserves, pastries, preserved fruits, meringues, etc. Feed additives: pig feed, sweeteners, etc. Daily chemical industry: toothpaste, mouthwash, eye drops, etc. Electroplating industry: Electroplating grade sodium saccharin is mainly used for electroplating nickel and used as a brightener. Adding a small amount of sodium saccharin can improve the brightness and flexibility of electroplated nickel. Specification: CERTIFICATE OF ANALYSIS Package

Anhui Sinotech company strictly select GMP products, support customer registration , and provide professional services to chemical customers in the global market.Purchase Sodium Benzoate Powder CAS NO.:532-32-1,inquiry Anhui Sinotech .   Name:  Sodium Benzoate Powder CAS No.:  532-32-1 Appearance: White crystalline powder Specification：Powder, extruded, ball/granualr Molecular formula: C7H5NaO2 Molecular Weight:  144.1032 Melting point: 300°C Boiling point: 249.3°C at 760 mmHg Water solubility: soluble Molecular structure: Description: Sodium benzoate powder CAS NO.:532-32-1, is an organic substance, the chemical formula is C7H5NaO2. It is a white crystalline powder. Odorless or slightly benzoin smell. The taste is slightly sweet and astringent. The relative molecular mass is 144.12. It is stable in the air, can absorb moisture in the air, and is easily soluble in water. The pH value of its aqueous solution is 8, and it is soluble in ethanol, glycerol and methanol. After sodium benzoate enters the body, it combines with glycine to form uric acid or with glucuronic acid to form glucuronic acid in the process of biotransformation. Both are excreted with urine and will not accumulate in the body. As long as it is within the normal dosage range, it is harmless to the human body and is a safe preservative. It can also be used in carbonated drinks, concentrated fruit juice, margarine, gum base, jam, jelly, soy sauce, etc. Application： Sodium benzoate powder CAS NO.: 532-32-1 1. Sodium benzoate is also an important preservative for acidic foods. It is converted into effective form of benzoic acid during application. See benzoic acid for scope of application and dosage. 2. Preservatives; antibacterial agents. 3. Sodium benzoate is a very important acidic feed preservative. It is converted into effective form of benzoic acid during application. See benzoic acid for scope of application and dosage. 4. This product is used as a food additive (preservative), a fungicide in the pharmaceutical industry, a dye mordant, a plasticizer in the plastic industry, and an organic synthesis intermediate for spices Specification: CERTIFICATE OF ANALYSIS Package