Gentamicin sulfate

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Gentamicin sulfate

2022-02-16

Gentamicin sulfate is an organic substance with the chemical formula C60H125O22N15·H2SO4, white or off-white crystalline powder, hygroscopic, easily soluble in water, insoluble in lipids, insoluble in organic solvents, stable in chemical properties, resistant to temperature The change of pH and pH is relatively stable, and the pH of 4% aqueous solution is 4.0 to 6.0.

Function and use
Clinically used for septicemia, respiratory tract infection, biliary tract infection, purulent peritonitis, intracranial infection, urinary tract infection caused by Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Shigella, Klebsiella, Proteus and other sensitive bacteria Infections and bacillary dysentery.

side effect
1 Similar to kanamycin, it has a greater impact on the vestibule of the ear, but less damage to the cochlea, mainly manifested as dizziness, vertigo and tinnitus. For renal insufficiency or children, more attention should be paid to toxic reactions, which can lead to hearing loss or even deafness in severe cases.
2 Because this product has a blocking effect on the neuromuscular junction, it is not suitable for intravenous injection or high-dose rapid intravenous infusion to prevent the occurrence of respiratory depression. [Contraindications] Those who are allergic to this product or other aminoglycosides are prohibited.

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